Total Restore by Gundry MD: Marketed for Gut-Lining Support

Leaky gut — intestinal hyperpermeability — is one of the most discussed topics in integrative wellness writing. When the tight junctions between intestinal cells break down, partially digested food particles, toxins, and bacterial fragments may enter the bloodstream. The downstream effects discussed in the literature can include joint pain, brain fog, skin conditions, fatigue, and food sensitivities.

I first encountered Total Restore while reading Dr. Steven Gundry's The Plant Paradox. I have written about this product as a consumer and wellness educator.

What Is Total Restore?

Total Restore by Gundry MD is a 20-ingredient gut-lining support formula. It holds Amazon's Choice status with a 4.0-star rating from over 9,300 reviews, with 1,000+ purchases per month.

Key ingredients include:

• L-Glutamine — the primary fuel for intestinal epithelial cells; essential for maintaining and repairing the gut lining
• N-Acetyl D-Glucosamine — a building block of the intestinal mucous layer; supports tight junction integrity
• Licorice Root Extract (DGL) — soothes the gut lining; reduces GI inflammation
• Zinc — critical for tight junction protein synthesis and gut barrier function
• Magnesium Beta-Hydroxybutyrate — supports cellular energy and ketone metabolism
• Grape Seed Extract — potent antioxidant; supports vascular integrity
• Cinnamon Bark — blood sugar regulation; anti-inflammatory
• Berberine HCl — modulates gut microbiome; anti-inflammatory and metabolic support
• Maitake Mushroom — immune modulation and gut microbiome support
• BioPerine — enhances absorption of all other ingredients by up to 20%

Keto-friendly, vegan, sugar-free, artificial sweetener-free.

Serving Information

The 90-capsule bottle provides a 30-day supply. Follow the label directions and consult your own clinician before use.

Some customers experience mild digestive adjustment in the first week as the gut microbiome shifts.

Also available on the [Holistic Human Shop](/shop#supplements).

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Affiliate link. General education only. Not medical advice. Consult your own clinician before starting any supplement.