Neprinol AFD: A Systemic Enzyme Formula for Cardiovascular & Immune Support

Most people think of enzymes as digestive aids. But systemic enzymes — taken on an empty stomach so they are absorbed into the bloodstream — perform a completely different set of functions. They circulate throughout the body, breaking down fibrin, modulating the immune response, reducing inflammation, and supporting cardiovascular health.

Neprinol AFD holds Amazon's Choice status with a 4.7-star rating from over 930 reviews, and over 800 people buy it every month.

What Is Neprinol AFD?

Neprinol AFD (Advanced Fibrin Defense) by Arthur Andrew Medical is a therapeutic-grade systemic enzyme blend containing:

• Serrapeptase (45,000 SPU per serving) — breaks down non-living tissue, fibrin, and scar tissue; supports sinus health and muscle recovery
• Nattokinase (15,000 FU per serving) — the most studied fibrinolytic enzyme; supports healthy blood viscosity and circulation
• Lipase — breaks down fats; supports cardiovascular health
• Protease — breaks down proteins and supports immune function
• Amla (Indian Gooseberry) — one of the richest natural sources of vitamin C; antioxidant and cardiovascular support
• Papain — proteolytic enzyme from papaya; anti-inflammatory
• Bromelain — from pineapple; anti-inflammatory and mucolytic
• Rutin — bioflavonoid that supports vascular integrity
• Coenzyme Q10 — essential for cellular energy production and cardiovascular health

The formula uses Arthur Andrew's proprietary Acid Armor capsules — enteric-coating-free, designed to resist stomach acid for superior absorption. Vegan, non-GMO, and kosher certified.

What Neprinol Does

Fibrin metabolism: Excess fibrin in the bloodstream is associated with poor circulation, scar tissue formation, and elevated cardiovascular risk. Customers report reductions in C-reactive protein, improved circulation, and relief from joint pain and stiffness.

Cardiovascular support: One Amazon reviewer — a naturopathic doctor — wrote: "Lower your blood pressure, thin your blood the safe way." Another: "C-reactive protein dropped from 12 to 7.5 and osteoarthritis in my knees is noticeably less painful."

Serving Information

Must be taken on an empty stomach — 45–60 minutes before eating, or at least 2 hours after a meal. Follow the label directions and consult your own clinician before use.

Important safety notes:

• Bleeding risk: Neprinol may increase bleeding risk, especially when combined with blood-thinning medications. Do not use if you have a bleeding disorder without consulting your physician.
• Pregnancy and nursing: Do not use if pregnant or nursing without consulting a healthcare provider.
• Surgery: Discontinue use at least 2 weeks before any scheduled surgery.

Also available directly from the manufacturer at [arthurandrew.com](https://arthurandrew.com/products/neprinol) and on the [Holistic Human Shop](/shop#supplements).

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Affiliate link. Educational purposes only. Consult your healthcare provider before starting any supplement.